국소 림프절 전이를 보이는 상악 평활근 육종에 대한 증례보고
A Case Report of Maxillary Leiomyosarcoma with Regional Lymph Node Metastasis
박숭, 김여갑, 이백수, 권용대, 최병준, 김영란,
소속 상세정보
박숭 ( Park Soong ) - 경희대학교 치과대학 구강악안면외과학교실
김여갑 ( Kim Yeo-Gap ) - 경희대학교 치과대학 구강악안면외과학교실
이백수 ( Lee Baek-Soo ) - 경희대학교 치과대학 구강악안면외과학교실
권용대 ( Kwon Yong-Dae ) - 경희대학교 치과대학 구강악안면외과학교실
최병준 ( Choi Byung-Jun ) - 경희대학교 치과대학 구강악안면외과학교실
김영란 ( Kim Young-Ran ) - 경희대학교 치과대학 구강악안면외과학교실
KMID : 0360120100320020183
Abstract
Leiomyosarcoma is a malignant neoplasm of smooth muscle origin and mostly originate from the wall of uterus and gastrointestinal tract, but primary leiomyosarcoma of the oral cavity is extremely rare. This tumor has a very poor prognosis due to high recurrence and metastasis rate, with 5 year survival rate of 32%. And regional lymph node metastasis is uncommon event. Complete wide surgical excision is the treatment of choice. A 64-year old man who had a painful ulcerative lesion on the labial & palatal gingiva of #11, 21 visited our department, and was diagnosed as leiomyosarcoma through a biopsy. Partial maxillectomy was carried out, with no following radiotherapy or chemotherapy. After months follow-up, there has been no evidence of recurrence or metastasis. But after months, we clinically find out two enlarged immobile palpable lymph node in right submandibular area of patient. So a biopsy was performed via an extraoral incision under local anesthesia. Histopathologic diagnosis diagnosis of the biopsy was lymph node metastasis of prior existed leiomyosarcoma. We report a case of a primary leiomyosarcoma occurred in a 64 year-old male patient involving the anterior maxillary region with regional lymph node metastasis with a review of literature.
키워드
Oral Leiomyosarcoma;Immunohistochemistry;Lymph node;Metastasis
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